Behind the Science

The Science Behind Reducing Allergens in Cats

"Research shows that eggs from chickens exposed to domestic shorthair cats can reduce Fel d1 allergens. Fel d1 is the major allergen found in cats, responsible for allergic reactions in up to 95% of people with cat allergies" (Ebenezer Satyaraj and colleagues 68-73, 2019)

What Is Fel d1?

Fel d1 is the primary allergen found in cats. This protein is present in their saliva and fur, triggering allergic reactions in sensitive individuals.

How Our Product Reduces Allergens

Chickens exposed to Fel d1 produce an antibody called "IGY" that attaches to the Fel d1 protein, reducing its effectiveness as an allergen. This results in lower allergen levels in cat fur and saliva.

Our Commitment to Ethical Practices

We ensure chickens are safely exposed to Fel d1, without harm. Through supervised interactions between cats and chickens, we maximize the production of anti-Fel d1 antibodies, all while keeping both animals safe during the process.

More Than Just Allergy Relief

Our product provides more than just allergen reduction:

Rich in protein, Linoleic acid, Vitamins B2, B12, and water-soluble Vitamin A.
Helps strengthen skin and coat health.
A nutritious, cost-effective, and convenient addition to your cat’s daily diet.

Still Researching, But Promising Results

While exact allergen reduction levels are still being studied, early findings are promising. Our egg-based supplement offers your cat a wealth of nutritional benefits, alongside potential allergen reduction.

Why Your Cat Will Love It

An easy way to boost your cat’s daily nutrition.
Potential to reduce allergens while promoting skin and coat health.
An affordable, simple addition to your cat’s diet.

Ready to Make a Difference?

Shop now to give your cat the allergen-reducing benefits and nutritional support they deserve!

Our Farm and Safety Procedures

At SAFELINE pet®, we prioritize the highest-quality products for feline health, starting with ethical sourcing. Our farmers follow USDA organic guidelines and strict biosecurity measures from the VDH and CDC. They provide a nutritious diet from a local, family-owned feed supplier. Our partnering farm, home to over 20 cats, ensures ethical exposure of chickens to the Fel d1 allergen, allowing cats to naturally cohabitate while protecting the flock from pests. We uphold humane and ethical care for all animals so you can confidently care for your cat.

Avian Influenza (H5N1) Safety Measures

We recognize concerns regarding H5N1 "Bird Flu." According to the Virginia Department of Health, no cases have been detected in Virginia’s domestic animals, including in Dayton and Roanoke, where we source our eggs. Facilities used by SaFeline pet® exclusively processes chicken eggs, eliminating cross-contamination risks.

Our Safety Process:

Pasteurization: Eggs are heated to 165°F with an immersion circulator, then rapidly cooled and freeze-dried.
Biosecurity: Fully enclosed coops, visitor restrictions, rodent control, routine cleaning, PPE use, and vigilant health monitoring safeguard our chickens and cats.

Our Process

We use a proprietary sugar blend to preserve beneficial egg proteins while deactivating harmful ones. This blend supports urinary tract health and allergy relief without affecting glucose levels, making it safe for diabetic cats.

For more information regarding Avian Influenza (H5N1): VDH, CDC, USDA

Citations:

Satyaraj, E., Gardner, C., Filipi, I., Cramer, K., & Sherrill, S. (2019). Reduction of active Fel d1 from cats using an antiFel d1 egg IgY antibody. Immunity, inflammation and disease, 7(2), 68–73. doi:10.1002/iid3.244

Satyaraj, E., Li, Q., Sun, P. & Sherrill, S. (2019). Anti-Fel d 1 immunoglobulin Y antibody-containing egg ingredient lowers allergen levels in cat saliva. Journal of Feline Medicine and Surgery, 21(10), 875-881. doi: 10.1177/1098612X19861218

Karlsson, M., Kollberg, H. & Larsson, A. (2004). Chicken IgY: utilizing the evolutionary difference. World’s Poultry Science Journal, 60, 341-348. doi: 10.1079/WPS200422

Schade, R., Calzado, E.G., Sarmiento, R., Chacana, P.A., Porankiewics-Asplund, J., Terzolo, H.R., (2005). Chicken egg yolk antibodies (IgY-technology): A review of progress in production and use in research and human and veterinary medicine. Alternatives to Laboratory Animals, 33(2),129-154.

Wedner, H.J., Mantia, T., Satyaraj, E., Gardner, C., Al-Hammadi, N. & Sherrill, S. Feeding cats egg product with anti-Fel d 1 antibodies decreases environmental Fel d 1 and allergic response. Manuscript in preparation.

Rahman, S., Nguyen S.V., Icatlo, F.C., Umeda, K. & Kodama Y. (2013). Oral passive IgY-based immunotherapeutics. Human Vaccines & Immunotherapeutics, 9, 1039-1048. doi: 10.4161/hv.23383

Kitties Love It!

I have 3 cats and they all go bananas for it! I use it every few days to make it last longer. I got it for my allergies and I haven't had a bad allergy day since I started using it! :)

Cats are loving it!

Ongoing with week three and cats are loving it. It adds flavor to their food and we've noticed a difference with my husband's allergies. I will be buying again !

My cat hates it

I had high hopes for this, but my cat only ate it once and now refuses to touch his food if added. Seems like there’s a lot of sugar in this too. Just another expensive product that yields nothing.

Hello James,

We are sorry to hear that your cat did not like the product. While we have hundreds of satisfied loyal customers, we cannot guarantee that the product will agree with every cat’s particular diet or preferences. Per the corresponding section on the FAQ page of our website, there is less than one gram of sugar in each jar; more specifically there’s less than .03 grams per serving (per one scoop).

Really works!

I started out feeding my cat with a name brand dog food which has this miracle allergy reducer in it. After realizing this cat food had grain in the ingredients, I chose to get a grain free cat food and added this egg powder to it. My son and I have bad allergies to cats but now we have no problems at all! I am so thankful that it is a natural remedy too!

Great product, nearly eliminated my allergies

Been a repeat customer for a while because, what can I say, this really works. It's not 100% elimination but it's the difference between having itchy eyes regularly and not feeling any symptoms most of the time.

1 2 3

FAQ

What ingredients are in the supplement?

Our product is an all-natural, simple formula made with whole eggs (whites and yolks without shells), sugar, and D-mannose (a natural sugar made from cranberries). That's it. No preservatives. No fillers. 100% natural.

When will my package ship after purchasing my order? When will I receive my package's tracking number?

Orders are expected to ship within 2-7 business days after the date the order was placed.
When you purchase our product, you will receive an initial confirmation email that your order was placed, billed, and received. After your order has shipped, you will receive another email with your order’s tracking number.

For any questions or concerns regarding your order, please email us at customerservice@safelinepet.com. In your email, always include each order number(s) for each order(s) you're referencing and the full name the order(s) was placed under.

How do I request a cancelation and refund of my order?

You MUST send an email to customerservice@safelinepet.com BEFORE THE ORDER IS SHIPPED to request a cancelation and full refund of your order. Your email must include the full name the order was placed under and the order number(s) for each corresponding order(s) you'd like us to issue a cancelation and refund for. We will reply to your email when we have issued the cancelation and full refund. When issued a refund, please allow a few days for the refund to be processed.

What is a Monthly Subscription Service? How do I request a refund/cancelation of my subscription order or pause/cancel my subscription service account?

Our Monthly Subscription Service offers an automatic monthly renewal of your selected order (1, 2, 3, or 4-pack) with FREE SHIPPING.

How it works: The monthly subscription service is received, billed, and automatically starts on the date that it is originally purchased. After the date it is purchased, a subscriber's order is expected to ship within 2-7 business days. On the same day each month following the date the monthly subscription service was placed, a subscriber receives an email that their order is automatically and simultaneously renewed, charged for, and billed, and is expected to ship within 2-7 business days after its renewed placement. A subscriber receives another email when their monthly subscription order has shipped, including the tracking number. This shipping confirmation email does NOT mean that a new order or charge has been placed.

How to request a refund and cancelation of your monthly subscription order: BEFORE THE ORDER IS SHIPPED, you MUST send an email to customerservice@safelinepet.com including the full name the subscription service is placed under and THE ORDER NUMBER(S) for each corresponding monthly subscription order(s) you're requesting a full refund and cancelation for. We will reply to your email request when we have issued the full refund and cancelation of your order(s). When issued a refund, please allow a few days for the refund to be processed.

How to pause or cancel your monthly subscription service account: Subscribers can adjust their monthly subscription service to meet their needs accordingly. Use your customer portal link found in your initial purchase confirmation email to make edits/changes to your account, including:

Skipping specified month(s) from being charged for or receiving monthly orders
Pausing your account indefinitely until you choose to automatically renew, be charged for, and receive your monthly subscription orders
Cancelling your account entirely to no longer automatically renew, be charged for, or receive monthly orders

If you cannot find your customer portal link or need assistance to access/edit your monthly subscription service account, send an email to customerservice@safelinepet.com.

PLEASE NOTE IF YOU PAUSE/CANCEL YOUR MONTHLY SUBSCRIPTION SERVICE ACCOUNT: ALWAYS SEND AN EMAIL after you pause/cancel your subscription service account, so we can reply confirming that it has successfully processed within our system. When you pause/cancel your monthly subscription service account, all monthly order(s) that were automatically renewed and charged for BEFORE THE DATE OF PAUSE/CANCELATION WILL STILL BE BILLED, SHIPPED, AND DELIVERED. For any outstanding monthly subscription order(s) you'd like us to issue a full refund and cancelation for BEFORE THE ORDER IS SHIPPED, you MUST send an email to customerservice@safelinepet.com specifically including THE ORDER NUMBER(S) for each corresponding monthly subscription order(s) you're requesting a refund and cancelation for. When issued a full refund of your order, please allow a few days for the refund to be processed.

How long does it take to feel a reduction in my allergy symptoms?

After around 3 weeks of daily feeding to your cat, you may start to feel relief from your cat allergy symptoms.

What are the directions for feeding my adult cat or kitten the supplement?

Feed it to your adult cat once a day everyday. Add one scoop (one teaspoon) of the powder supplement into your cat’s wet or dry food and mix thoroughly. Add a little bit of water to the dry food if the powder supplement is not adhering. For kittens under 10 months old, mix in a half scoop (1/2 teaspoon) to their wet/dry food.

Is the food topper safe and effective for my adult cat or kitten? What are the health benefits?

Yes, our product is safe and effective for adult cats and kittens. Our formula is designed to promote feline digestive, urinary tract, and coat health.

How much sugar is in the product?

The sugar is added to protect the allergen-neutralizing proteins in the eggs through the freeze drying process. There is less than 1 gram of sugar in each jar. The sugar is added to protect the proteins in the egg from becoming de-natured during the freeze-drying process. 3% is the recommended sugar limit in a cat's daily diet. Our sugar amount is below this limit while still remaining effective.

What research have you done to formulate the supplement?

All of our research sources can be found on the ‘How it Works’ page here.

What safety and health measures are included in your manufacturing process?

Our farms and operations are based out of Dayton and Roanoke, Virginia. Both co-owners have professional experience in the food service industry and follow all Current Good Manufacturing Practice (CGMP), Virginia Department of Health (VDH), and Center for Disease Control (CDC) guidelines. SaFeline pet and our farmers follow biosecurity measures, including, but not limited to, sanitizing utensils before/after use, using stainless steel surfaces and materials, wearing PPE, and minimizing cross-contamination.