Behind the Science

 

The Science Behind Reducing Allergens in Cats

"Research shows that eggs from chickens exposed to domestic shorthair cats can reduce Fel d1 allergens. Fel d1 is the major allergen found in cats, responsible for allergic reactions in up to 95% of people with cat allergies" (Ebenezer Satyaraj and colleagues 68-73, 2019)

What Is Fel d1?

Fel d1 is the primary allergen found in cats. This protein is present in their saliva and fur, triggering allergic reactions in sensitive individuals.

How Our Product Reduces Allergens

Chickens exposed to Fel d1 produce an antibody called "IGY" that attaches to the Fel d1 protein, reducing its effectiveness as an allergen. This results in lower allergen levels in cat fur and saliva.

Our Commitment to Ethical Practices

We ensure chickens are safely exposed to Fel d1, without harm. Through supervised interactions between cats and chickens, we maximize the production of anti-Fel d1 antibodies, all while keeping both animals safe during the process.

More Than Just Allergy Relief

Our product provides more than just allergen reduction:

  • Rich in protein, Linoleic acid, Vitamins B2, B12, and water-soluble Vitamin A.
  • Helps strengthen skin and coat health.
  • A nutritious, cost-effective, and convenient addition to your cat’s daily diet.

Still Researching, But Promising Results

While exact allergen reduction levels are still being studied, early findings are promising. Our egg-based supplement offers your cat a wealth of nutritional benefits, alongside potential allergen reduction.

Why Your Cat Will Love It

  • An easy way to boost your cat’s daily nutrition.
  • Potential to reduce allergens while promoting skin and coat health.
  • An affordable, simple addition to your cat’s diet.

Ready to Make a Difference?

Shop now to give your cat the allergen-reducing benefits and nutritional support they deserve!

Our Farm and Safety Procedures 

At SAFELINE Pet, we prioritize the highest-quality products for feline health, starting with ethical sourcing. Our farmers follow USDA organic guidelines and strict biosecurity measures from the VDH and CDC. They provide a nutritious diet from a local, family-owned feed supplier. Our partnering farm, home to over 20 cats, ensures ethical exposure of chickens to the Fel d1 allergen, allowing cats to naturally cohabitate while protecting the flock from pests. We uphold humane and ethical care for all animals so you can confidently care for your cat.

Avian Influenza (H5N1) Safety Measures

We recognize concerns regarding H5N1 "Bird Flu." According to the Virginia Department of Health, no cases have been detected in Virginia’s domestic animals, including in Dayton and Roanoke, where we source our eggs. SAFELINE’s facility exclusively processes chicken eggs, eliminating cross-contamination risks.

Our Safety Process:

  • Pasteurization: Eggs are heated to 165°F with an immersion circulator, then rapidly cooled and freeze-dried.
  • Biosecurity: Fully enclosed coops, visitor restrictions, rodent control, routine cleaning, PPE use, and vigilant health monitoring safeguard our chickens and cats.

Our Process

We use a proprietary sugar blend to preserve beneficial egg proteins while deactivating harmful ones. This blend supports urinary tract health and allergy relief without affecting glucose levels, making it safe for diabetic cats.

For more information regarding Avian Influenza (H5N1): VDH, CDC, USDA

Citations:

Satyaraj, E., Gardner, C., Filipi, I., Cramer, K., & Sherrill, S. (2019). Reduction of active Fel d1 from cats using an antiFel d1 egg IgY antibody. Immunity, inflammation and disease, 7(2), 68–73. doi:10.1002/iid3.244

Satyaraj, E., Li, Q., Sun, P. & Sherrill, S. (2019). Anti-Fel d 1 immunoglobulin Y antibody-containing egg ingredient lowers allergen levels in cat saliva. Journal of Feline Medicine and Surgery, 21(10), 875-881. doi: 10.1177/1098612X19861218

Karlsson, M., Kollberg, H. & Larsson, A. (2004). Chicken IgY: utilizing the evolutionary difference. World’s Poultry Science Journal, 60, 341-348. doi: 10.1079/WPS200422

Schade, R., Calzado, E.G., Sarmiento, R., Chacana, P.A., Porankiewics-Asplund, J., Terzolo, H.R., (2005). Chicken egg yolk antibodies (IgY-technology): A review of progress in production and use in research and human and veterinary medicine. Alternatives to Laboratory Animals, 33(2),129-154.

Wedner, H.J., Mantia, T., Satyaraj, E., Gardner, C., Al-Hammadi, N. & Sherrill, S. Feeding cats egg product with anti-Fel d 1 antibodies decreases environmental Fel d 1 and allergic response. Manuscript in preparation.

Rahman, S., Nguyen S.V., Icatlo, F.C., Umeda, K. & Kodama Y. (2013). Oral passive IgY-based immunotherapeutics. Human Vaccines & Immunotherapeutics, 9, 1039-1048. doi: 10.4161/hv.23383

Customer Reviews

Based on 52 reviews
77%
(40)
6%
(3)
4%
(2)
2%
(1)
12%
(6)
C
Casey McCaffrey
Great product

Product makes a difference with our allergies and cats love the taste. Only complaint is the shipping time.

L
Laura
Really works

It really works

m
m.b.

Great product no issues with product, cat eats with wet food each night. Very pleased with results. Took extended time to receive product with second order.

Y
Yunuen
Never shipped

I placed an order for two cat egg powders on May 26, and it’s now June 20. It still hasn’t even shipped. I sent an email yesterday and haven’t received any response. At this point, the lack of communication and the extreme delay are beyond frustrating. It’s honestly outrageous to wait this long with absolutely no update. I’ve never experienced anything like this, and I’m extremely disappointed.

Hi Yunuen,

We are so sorry for the delay with your order and for the lack of communication, we completely understand your frustration, and you’re absolutely right to feel disappointed.

We’re a very small team of just two people, balancing this business alongside full-time jobs to help make ends meet. While that’s no excuse for the delay or the lack of updates, we do want to be transparent and let you know that your order was held up due to an unexpected issue in our manufacturing process. The good news is that the issue has now been resolved, and we’re working hard to get your order, and all others, out as soon as possible.

As a small token of apology, we’ve refunded your shipping costs for the inconvenience. We know this doesn’t make up for the wait or the silence, but please know how truly sorry we are. Your support means the world to us, and we’re doing everything we can to make things right.

Thank you so much for your patience.

Warm regards,
SaFeline pet

M
Molly Olsen

Working great so far

FAQ

What ingredients are in the supplement?

Simply chicken eggs exposed to cat allergens and our proprietary sugar blend. No fillers or preservatives. 

When will my package arrive after placing the order?

**PLEASE NOTE—
Orders will be shipped within 10 business days of when the order is placed. Due to unforeseen manufacturing issues we’re currently experiencing, we cannot expedite the shipping process or ensure an adequately-timed and earlier delivery for subscription orders to prevent running out between months.

We deeply understand your frustration on this issue and appreciate your feedback. We are proactively addressing these issues surrounding shipping and subscriptions to best serve our customers and their feline friends.

Thank you for your support and patience as we work out the kinks and generate solutions.**

How can I access or make edits to my subscription purchase?

Customers who have purchased a subscription can access and edit their customer subscription through the link sent via email. We are in the process of creating a ‘Subscription Portal’ page on our website to streamline the accessibility and editing on customers’ end. If you need help accessing or editing your customer subscription portal, please email us as customerservice@safelinepet.com

How long does it take to feel a reduction in my allergy symptoms?

After around 3 weeks of daily feeding to your cat, you may start to feel relief from your cat allergy symptoms. 

What are the directions for feeding my cat the supplement?

Feed it to your cat once a day everyday. Add one scoop (one teaspoon) of the powder supplement into your cat’s wet or dry food and mix thoroughly. Add a little bit of water to the dry food if the powder supplement is not adhering. For kittens under 10 months old, mix in a half scoop (1/2 teaspoon) to their wet/dry food. 

Is SaFeline pet’s food topper safe for my cat?

Yes, our product is safe for cats. It's an all-natural, simple formula made with eggs, sugar, and D-mannose (a natural sugar made from cranberries). That's it. No preservatives. No fillers. 100% natural.

How much sugar is in the product?

The sugar is added to protect the allergen-neutralizing proteins in the eggs through the freeze drying process. There is less than 1 gram of sugar in each jar. The sugar is added to protect the proteins in the egg from becoming de-natured during the freeze-drying process. 3% is the recommended sugar limit in a cat's daily diet. Our sugar amount is below this limit while still remaining effective.

What research have you done to formulate the supplement?

All of our research sources can be found on the ‘How it Works’ page here.

What safety and health measures are included in your manufacturing process?

Our farms and operations are based out of Dayton and Roanoke, Virginia. Both co-owners have professional experience in the food service industry and follow all Current Good Manufacturing Practice (CGMP), Virginia Department of Health (VDH), and Center for Disease Control (CDC) guidelines. SaFeline pet and our farmers follow biosecurity measures, including, but not limited to, sanitizing utensils before/after use, using stainless steel surfaces and materials, wearing PPE, and minimizing cross-contamination.

Do you ship internationally?

No, we currently do not ship outside of the USA.