How SaFeline pet Targets Cat Allergens

Chickens can produce special egg antibodies called IgY that are designed to bind to Fel d 1, the main protein in cats that causes allergies. When cats eat food containing these antibodies, the IgY can attach to Fel d 1 in their saliva and reduce how much active allergen is spread onto their fur, which may lower environmental exposure to the allergen (Satyaraj et al., 2019).

Fel d 1 is the main protein that causes cat allergies. It is made in cats’ skin glands and saliva. When cats groom themselves, the protein spreads onto their fur and into the air as tiny particles called dander. In people who are allergic, the immune system reacts to Fel d 1 as if it were harmful, which leads to symptoms like sneezing, runny nose, and itchy eyes (Nielsen et al., 2010).

Scientists explain that the main cat allergen, called Fel d 1, is a protein made by cats in their skin and saliva. When cats groom themselves, this protein spreads onto their fur and into the environment. New research shows that special antibodies called IgY, which are made in chickens, can be used to bind to Fel d 1 and reduce its active form. These antibodies are produced when chickens are exposed to Fel d 1 in a controlled way, and they are collected from egg yolks. When cats eat food containing these IgY antibodies, the antibodies can attach to Fel d 1 in the cat’s saliva and lower how much active allergen is spread around (Hossenbaccus et al., 2022).

Scientists found that when chickens are given a safe, controlled exposure to a cat allergen called Fel d 1, their bodies make special proteins called IgY antibodies. These antibodies go into the egg yolks. When cats eat these egg-based ingredients, the antibodies can bind to Fel d 1 and reduce how active the allergen is on the cat’s fur (Matulka et al., 2020). SaFeline pet is committed to partnering with farms that uphold ethical farming practices and ensuring our manufacturing facility follows stringent health and safety precautions.

How SaFeline pet Reduces Cat Allergens

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Cats naturally produce an allergen

Cats produce a protein called Fel d 1 in their saliva. When they groom, it spreads across their fur and into your home, causing you to sneeze and sniffle.

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Chickens develop antibodies to the allergen

When chickens are exposed to Fel d 1, their immune system produces antibodies called IgY.

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IgY antibodies passed down into chicken eggs

Anti-Fel d 1 antibodies produced in the egg yolks are processed into an easily-digestible powder for your cat’s enjoyment and your allergy relief.

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Your cat consumes it daily

SaFeline is added to your cat's food. The IgY antibodies interact with Fel d 1 in your cat's saliva.

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Allergen production reduced at the source

This small change to your cat’s diet can work to minimize the production and spread of Fel d 1 allergens in your home.

Designed to Support More Than Allergen Reduction

SaFeline is designed to support allergen reduction while also contributing to your cat’s everyday wellness through simple daily nutrition.

Healthy source of protein

Healthy source of protein

Eggs are a high-quality and easily-digestible source of protein in your cat’s daily diet.

Supports feline skin and coat health

Supports feline skin and coat health

Formulated with supportive and natural ingredients to help maintain a shiny fur coat.

Supports normal, healthy feline urinary tract function

Supports normal, healthy feline urinary tract function

A small dose of the natural sugar D-mannose into your cat’s daily diet supports the natural self-cleaning and regulation of their bladder.

Promising Research, Backed by Science

Peer-reviewed scientific research into the interaction of IgY antibodies and Fel d 1 is ongoing, and published findings and results are encouraging. SaFeline pet is designed around the emerging science to help support allergen reduction through a simple daily routine that offers nutritional benefits for your cat.

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Our Farm & Safety Standards

At SaFeline pet, a quality product starts with responsible sourcing and ethical animal care. Our partnering farms follow high standards for cleanliness, nutrition, and biosecurity, with practices informed by USDA-aligned guidelines and recommendations.

Our chickens are naturally exposed to feline allergens through the safe cohabitation with cats in a controlled farm environment. This humane cohabitation between chickens and cats allows our chickens to naturally produce IgY antibodies into their egg yolks.

Every batch is carefully processed and manufactured in our USA-based facility that follows Good Manufacturing Practices (GMP) standards to ensure safety, consistency, and quality in every unit.

Avian Influenza (H5N1) Safety Standards

SaFeline pet and our egg suppliers are committed to maintaining strict sourcing and processing safety standards. Our manufacturing facility and partnering farms follow established biosecurity and safety protocols designed to protect your and your cat’s health. Our manufacturing facility exclusively processes chicken eggs, thereby minimizing the risk of cross-contamination throughout the production process.

A better way to care for your cat

A simple way to support allergen reduction, clean nutrition, and everyday comfort for both you and your cat.

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Biosecurity

Our partnering farms follow safety and security standards, including PPE use and the routine cleaning and monitored access of the enclosed chicken coops.

Pasteurization

We heat-treat our eggs by cooking them fully to 165℉.

Freeze Drying

We freeze dry our egg blend to preserve the nutritional value and ensure a convenient storage with a stable shelf life.

urinary health support 🥚
carefully processed 🥚
allergen-driven formula 🥚
made for cats 🥚
clean ingredients 🥚
science-backed solution 🥚
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SaFeline pet®
Sora Snyder
Seemed nice but cat stopped eating it

We slowly added it to her food like it says to and for a couple of weeks, she was eating it well and it seemed to be working. Her fur texture changed and it may have been a placebo, but I did seem to sneeze less around her.

A month or two has passed and she now refuses to eat it. She's eating around it and avoiding any tricks to hide it in her food. I guess she just doesn't like the taste ¯\_(ツ)_/¯

Oh well, cats are notoriously picky eaters so I wouldn't blame the company. I would recommend waiting before you subscribe to any potential buyers, though. I have no clue what I'm going to do with these extra jars.

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SaFeline pet®
Tyler b.

This product has made a huge difference for my allergies. We first adopted our cat 7 years ago, and I've suffered with "allergy overflow" days (maybe once a week or once every other week) where my allergies would be debilitating for at least a day, sometimes two. Since using this food topper, those days have completely disappeared. Highly recommend this product to anyone that has a cat at home! Also, the company is very responsive to customer service requests and extremely kind, thoughtful, and willing to help. They've secured me as a customer for life.

My kitty has made me itchy for years and I've just dealt with it. Now I have my son and he inherited my allergy... we started our kitty on this topper and are never going back! We can let him snuggle and head butt and it doesn't bother us one bit. 💗

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SaFeline pet®
Malia W.

I just received the 30 day supply, but have not tried it yet. Writing a review to let people know that shipping does take a very long time - I ordered on August 28th and received on November 6th. I was starting to feel like maybe I got scammed, but it was not the case! I am looking forward to trying the product and updating my review after the 30 days. I already feed my cat the Purina LiveClear allergen reducing dry food that deactivated the Fel d1, however since I started supplementing with wet food I don't think it's as effective. Hoping that adding this to my cat's wet food will really make a difference.

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SaFeline pet®
Gretchen P

I started adding this topper to my cat's food when i got him as a kitten a year and a half ago. I have cat allergies and hoped this would help. It wasn't until a shipping delay at SaFeline caused me to go without it for a few weeks that I realized just how much of a difference this product makes. Without it I gradually started getting more sneezy and congested and my eyes were a mess. Within a few days of regularly using it again my symptoms are gone. I'll be a customer for life! Also, the delay was unavoidable - parts do break and replacements can be hard to get quickly these days, particularly for small businesses. Their communication was great and I'm delighted they're back up to speed. This is a terrific business, kudos Matt and Seth :)

I doubt they will approve and publish this review, but I may as well try. I was happy with this product before they kept delaying my subscription shipments and billing me regardless. The point of using the product is to eliminate allergens, which means the product must be used consistently. With unforeseen, very extended delays, this is impossible even with trying to order extra to create a time buffer. I run out, and the allergen rebounds, rendering the product pointless and useless by the time I get my next supply. Very unreliable and frustrating.

It works! No longer experiencing red itchy eyes, sneezing, or hives. It’s like my cats magically turned hypoallergenic. One of my cats loves it by itself; but I mix it in with a churro lick treat for the picky cat.

FREQUENTLY ASKED QUESTIONS

  • When will my package ship after purchasing my order? When will I receive my package's tracking number?

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    Orders are expected to ship within 2-7 business days after the date the order was placed.
    When you purchase our product, you will receive an initial confirmation email that your order was placed, billed, and received. After your order has shipped, you will receive another email with your order’s tracking number.

    For any questions or concerns regarding your order, please email us at customerservice@safelinepet.comIn your email, always include each order number(s) for each order(s) you're referencing and the full name the order(s) was placed under.

  • How do I request a cancelation and refund of my order?

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    You MUST send an email to customerservice@safelinepet.com BEFORE THE ORDER IS SHIPPED to request a cancelation and full refund of your order. Your email must include the full name the order was placed under and the order number(s) for each corresponding order(s) you'd like us to issue a cancelation and refund for. We will reply to your email when we have issued the cancelation and full refund. When issued a refund, please allow a few days for the refund to be processed.

  • What is a Monthly Subscription Service? How do I request a refund/cancelation of my subscription order or pause/cancel my subscription service account?

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    Our Monthly Subscription Service offers an automatic monthly renewal of your selected order (1, 2, 3, or 4-pack) with FREE SHIPPING.

    How it works: The monthly subscription service is received, billed, and automatically starts on the date that it is originally purchased. After the date it is purchased, a subscriber's order is expected to ship within 2-7 business daysOn the same day each month following the date the monthly subscription service was placed, a subscriber receives an email that their order is automatically and simultaneously renewed, charged for, and billed, and is expected to ship within 2-7 business days after its renewed placement. A subscriber receives another email when their monthly subscription order has shipped, including the tracking number. This shipping confirmation email does NOT mean that a new order or charge has been placed.

    How to request a refund and cancelation of your monthly subscription order: BEFORE THE ORDER IS SHIPPED, you MUST send an email to customerservice@safelinepet.com including the full name the subscription service is placed under and THE ORDER NUMBER(S) for each corresponding monthly subscription order(s) you're requesting a full refund and cancelation for. We will reply to your email request when we have issued the full refund and cancelation of your order(s). When issued a refund, please allow a few days for the refund to be processed.

    How to pause or cancel your monthly subscription service account: Subscribers can adjust their monthly subscription service to meet their needs accordingly. Use your customer portal link found in your initial purchase confirmation email to make edits/changes to your account, including:

    • Skipping specified month(s) from being charged for or receiving monthly orders
    • Pausing your account indefinitely until you choose to automatically renew, be charged for, and receive your monthly subscription orders
    • Cancelling your account entirely to no longer automatically renew, be charged for, or receive monthly orders

    If you cannot find your customer portal link or need assistance to access/edit your monthly subscription service account, send an email to customerservice@safelinepet.com.

    PLEASE NOTE IF YOU PAUSE/CANCEL YOUR MONTHLY SUBSCRIPTION SERVICE ACCOUNT: ALWAYS SEND AN EMAIL after you pause/cancel your subscription service account, so we can reply confirming that it has successfully processed within our system. When you pause/cancel your monthly subscription service account, all monthly order(s) that were automatically renewed and charged for BEFORE THE DATE OF PAUSE/CANCELATION WILL STILL BE BILLED, SHIPPED, AND DELIVERED. For any outstanding monthly subscription order(s) you'd like us to issue a full refund and cancelation for BEFORE THE ORDER IS SHIPPED, you MUST send an email to customerservice@safelinepet.com specifically including THE ORDER NUMBER(S) for each corresponding monthly subscription order(s) you're requesting a refund and cancelation for. When issued a full refund of your order, please allow a few days for the refund to be processed.

  • What ingredients are in the supplement?

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    Our product is an all-natural, simple formula made with whole eggs (whites and yolks without shells), sugar, and D-mannose (a natural sugar made from cranberries). That's it. No preservatives. No fillers. 100% natural.
  • How long does it take to feel a reduction in my allergy symptoms?

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    After around 3 weeks of daily feeding to your cat, you may start to feel relief from your cat allergy symptoms.
  • What are the directions for feeding my adult cat or kitten the supplement?

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    Feed it to your adult cat once a day everyday. Add one scoop (one teaspoon) of the powder supplement into your cat’s wet or dry food and mix thoroughly. Add a little bit of water to the dry food if the powder supplement is not adhering. For kittens under 10 months old, mix in a half scoop (1/2 teaspoon) to their wet/dry food.
  • Is the food topper safe and effective for my adult cat or kitten? What are the health benefits?

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    Yes, our product is safe and effective for adult cats and kittens. Our formula is designed to promote feline digestive, urinary tract, and coat health.
  • How much sugar is in the product?

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    There is less than 1 gram of sugar in each jar. The sugar is added to protect the proteins in the egg from becoming de-natured during the freeze-drying process. 3% is the recommended sugar limit in a cat's daily diet. Our sugar amount is below this limit while still remaining effective.
  • What research have you done to formulate the supplement?

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    All of our research sources can be found on the ‘How it Works’ page
  • What safety and health measures are included in your manufacturing process?

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    Our farms and operations are based out of Dayton and Roanoke, Virginia. Both co-owners have professional experience in the food service industry and follow all Current Good Manufacturing Practice (CGMP), Virginia Department of Health (VDH), and Center for Disease Control (CDC) guidelines. SaFeline® pet and our farmers follow biosecurity measures, including, but not limited to, sanitizing utensils before/after use, using stainless steel surfaces and materials, wearing PPE, and minimizing cross-contamination.
  • Do you ship internationally?

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    No, we currently do not ship outside of the USA.